Confused About Folate?

Green Vegetables

At the risk of sounding redundant, I am making folic acid the topic of yet another article. Why? Because making sure you are getting enough folate is one of the most important things you can do for your health. Yet if you read the headlines lately, you may be running scared from folate. Should you take folate or shouldn’t you, and if so, how much should you take? Let’s clear up some of the confusion.

First, the nomenclature. Folate is the natural form of the nutrient that is found in foods. Folic acid is the synthetic form that is used in many vitamins and for fortification of foods.

Remember, folate is the main nutrient involved in the repair and maintenance of our DNA, and that’s why it is involved in everything from cancer, to birth defects, to cervical dysplasia. Studies show that getting enough folate may help protect against several types of cancer, especially colon cancer.

And as Jim’s article discussed, taking in adequate folate protects women who consume low to moderate amounts of alcohol from breast cancer. Folate also helps ensure that we have adequate levels of SAMe, which plays a role in mood, protecting against devastating depression. And while many families are debating whether their young daughters should take an HPV vaccine to protect against cervical cancer, it goes completely un-heralded that folate reduces cervical cancer risk significantly.1

Because of a high rate of neural tube defects, the United States decided in 1998 to start fortifying foods with folic acid, and it has been very successful.2 But some studies have found that getting too much folic acid may increase cancer risks slightly in adults, and these are the headlines that have people running scared. Moreover, recent studies which found that folic acid didn’t lower risk of heart disease have led to headlines that are implying, “Hey, don’t bother with folate.”

Some important clarifications about this topic were made in the newsletter from the Harvard School of Public Health, called The Nutrition Source. First and foremost, they point out that the increased cancer risks are slight, and that they are linked primarily to the over consumption of folic acid from fortified foods like cereals and pasta.

The newsletter explained that the reason for the increased health risks may be that at very high intakes of folic acid, the body can’t process it all into the active form, and the presence of the unconverted folate prevents uptake of converted folate into the brain and other tissues.

The risks of too much folate from fortified foods though small, deserve further study, but the experts at Harvard aptly point out that the vast majority of the evidence shows that “humans show a lower risk of colon and breast cancer with greater intakes of folate or folic acid,” — not an increased risk.3

Folate from foods poses no health risks, possibly because its absorption and efficacy are enhanced by the presence of other nutrients in the foods. The folks at Harvard recommend taking a multivitamin with 400 mcg of folate, and also making sure to eat plenty of natural food sources of folate.

The multivitamin is especially important if you know you are not eating enough fruits, vegetables, beans, nuts and seeds each day. For people who consume alcohol regularly, they recommend getting at least 600 mcg of folate per day.4 This is especially important for women.

But how are we to get enough folate without getting too much from over-fortified cereals and pastas? It really isn’t that hard. As you can see from the list below, 5-6 servings of fruits and vegetables per day should cover it!

Natural Sources of folate:5,6

Beef liver, 3 oz (I recommend organic only) — 185 mcg


Black-eyed peas, ½ cup cooked — 105 mcg


Spinach, ½ cup cooked —100 mcg


Great Northern beans, ½ c. cooked — 90 mcg


Asparagus, 5 spears — 100 mcg


Turnip greens, ½ cup — 80 mcg


Strawberries, 8 medium-sized — 80 mcg


Brussels sprouts, ½ cup cooked — 80 mcg


Broccoli, 1 cup cooked —100 mcg


References

  1. http://cancerres.aacrjournals.org/cgi/content/full/64/23/8788.
  2. Lumley, J, et al. (2001) Cochrane Database Syst. Rev. 3CD001056.
  3. http://www.hsph.harvard.edu/nutritionsource/what-should-you-eat/folic-acid/index.html#1.
  4. http://www.hsph.harvard.edu/nutritionsource/what-should-you-eat/vitamin-b/index.html.
  5. http://ods.od.nih.gov/factsheets/folate.asp.
  6. http://www.folicacidnow.net/foodSources.html#four.

[Ed. Note: Laura B. LaValle, RD, LD is presently the director of dietetics nutrition at LaValle Metabolic Institute. Laura and her husband, Jim LaValle, R.Ph, CCN, ND have developed the powerful and life-changing Metabolic Code Dietcontaining step-by-step, easy to follow recommendations for harnessing optimal metabolic energy and turning your body’s chemical make up into a fat-burning furnace. To learn more click here now.]

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2 Responses to “Confused About Folate?”

  1. Diane Rundell Says:

    THANK YOU for this article!!! I have been confused by the folate/folic acid words forever. This totally explains it and now I finally understand.
    Love the newsletter; I am fascinated by health/wellness issues, even though I have a weight ‘issue’ that seems to be the combination of genetic and sugar-craving/methyl-deficient diet… James’ article in this newsletter was also wonderful, and you might tell him so!
    Thanks again - I love the articles, and learn so much from them.
    Best regards,
    Diane Rundell

  2. Jeff Coleman Says:

    Thanks for the clarification on folate. However, it did rais one question for me: is it possible to get a folate supplement, or is folic acid the only option?

    Thanks,
    Jeff

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